Current Grant Opportunity View - GO8535

The Medical Research Future Fund (MRFF) Clinical Trials Activity (CTA) Initiative and National Health and Medical Research Council (NHMRC) 2025 Australia-UK Platform Studies in Areas of Unmet Clinical Need aims to support research in shared areas of interest in Australia and the UK. The purpose of the collaboration is to support joint Australia-UK platform trials, where the Australian-based component is funded through the MRFF or the NHMRC, and the UK-based component is funded through the NIHR UK.

The objective of this grant opportunity is to support new, adaptive platform trials (Phase 2 or 3) in areas of unmet clinical need. The platform must be internationally collaborative, with joint project leads based in Australia (for the Australian-based component of the trial) and the UK (for the UK-based component of the trial).

The intended outcome of the research is to invest in new, ambitious platform trials in areas of unmet clinical need that support increased access to high-quality, evidence-based and effective health care.

To apply to MRFF or NHMRC, applicants must have applied for funding to the NIHR UK as required under their official call specification. Applicants with Stage 1 and Stage 2 applications assessed as fundable by the NIHR UK must be invited to apply for either MRFF or NHMRC funding. Further information on the grant opportunity is available from the NHMRC website.

The MRFF funding for grant opportunity is being administered by NHMRC on behalf of the Australian Government Department of Health, Disability and Ageing.

Further information on the Medical Research Future Fund is available from the Department of Health, Disability and Ageing's website.

A list of Eligible Organisations can be found on the NHMRC List of MRFF Eligible Organisations webpage. A list of Administering Institution can be found on the NHMRC  Administering Institutions webpage.

Applications will only be accepted from invited applicants via an approved MRFF Eligible Organisations and NHMRC Administering Institutions.

A list of approved MRFF Eligible Organisations is available from the MRFF Eligible Organisations List on the NHMRC website.

A list of NHMRC approved Administering Institutions is available at: https://www.nhmrc.gov.au/funding/manage-your-funding/nhmrc-funding/administering-institutions

Applications must satisfy all the requirements set out in the MRFF CTA and NHMRC 2025 Australia UK Platform Studies in Areas of Unmet Clinical Need Grant Guidelines

(as per grant guidelines)

$15,000,000.00

From $0.00 to $5,000,000.00

Applicants who have been invited to apply are advised to read the Grant Guidelines and associated supplementary materials thoroughly and liaise with the MRFF Eligible Organisation or NHMRC Administering Institution that will submit the application to identify any specific requirements that the Organisation might have.

Applications must be submitted electronically using NHMRC’s online granting system (Sapphire). Applicants must be invited to apply for either MRFF or NHMRC funding.

Questions should be submitted no later than 1:00pm (ACT Local Time) on 19 August 2026