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Archived Grant Opportunity View - GO5815

MRFF – PPHRI – 2022 Assessment of High-Cost Gene Treatments and Digital Health Interventions Grant Opportunity

Contact Details

NHMRC Research Help Centre

1800 500 983



National Health and Medical Research Council (NHMRC)
Close Date & Time:
1-Mar-2023 5:00 pm (ACT Local Time)
Show close time for other time zones
Co-sponsored with:
Department of Health and Aged Care
Internal Reference ID:
Primary Category:
231013 - Medical Research
Publish Date:
Selection Process:
Targeted or Restricted Competitive


The objective of the Grant Opportunity is to provide grants of financial assistance to support medical research and medical innovation projects that:

  • Stream 1 (Targeted Call for Research (TCR):  develop a generalisable model to support assessment and validation of the clinical effectiveness and cost-effectiveness of new and emerging high upfront-cost therapeutics which includes consideration of ethical, legal, social and cultural aspects.
  • Stream 2 (TCR): conduct an implementation trial in both rural/remote and major city settings utilising the continuous remote monitoring capabilities of pacemakers and implantable cardioverter defibrillators to assess their health and non-health outcomes such as patient preferences, usability and cost effectiveness and appropriateness.
  • Stream 3 (TCR): undertake a retrospective or prospective evaluation of an implementation of a digital health intervention in order to assess the relative impact of augmenting face-to-face care with data from digital tools that advances assessment methods for digital innovations.

The intended outcome of the grant opportunity is to improve the health and wellbeing of Australians by:

  • Stream 1: informing decision making about the assessment of new and emerging high upfront-cost therapeutics for the Australian health care system.
  • Stream 2: generating evidence that will support clinically effective, safe, and cost-effective implementation of remote cardiac monitoring.
  • Stream 3: generating evidence that will support the effective implementation of digital innovations that augment face-to-face care.

Applicants to this grant opportunity must propose research that addresses one of the three Streams of research only. Applicants must specify the Stream to which they are applying in their application.

Further information on the Medical Research Future Fund is available from the Department of Health and Aged Care’s website


Applications will only be accepted from approved MRFF Eligible Organisations. A list of approved MRFF Eligible Organisations is available from the GrantConnect GO Documents and from the MRFF Eligible Organisations List  on the NHMRC website.

Applications must satisfy all the requirements set out in the Medical Research Future Fund (MRFF) – Preventive and Public Health Research Initiative – 2022 Assessment of High-Cost Gene Treatments and Digital Health Interventions Grant Opportunity Guidelines.

Grant Activity Timeframe:

The maximum grant duration is 4 years.

Total Amount Available (AUD):


Estimated Grant Value (AUD):

From $0.00 to $1,500,000.00

Instructions for Application Submission:

Applicants are advised to read the Grant Guidelines thoroughly and liaise with the MRFF Eligible Organisation that will submit the application to identify any specific requirements that the Organisation might have.

Applications must be submitted electronically using NHMRC’s online granting system (Sapphire).

Other Instructions:

Minimum Data closes at 5:00 pm (ACT Local Time) on 31 January 2023.

Questions should be submitted no later than 1:00 pm (ACT Local Time) on 22 February 2023.

Contact Details

NHMRC Research Help Centre

1800 500 983