Closed Grant Opportunity View - GO8294

The objective of this GO is to provide grants of financial assistance to support medical research and medical innovation projects that:

Stream 1 (TCR): develop genomic tools and technologies to identify genetic predisposition to cancer and improve screening and targeted intervention. Focus on increased access to genomic testing and on liquid biopsy.

Stream 2 (TCR): conduct scalable research to enhance novel gene discoveries, increase diagnostic rates and enable disease modelling to support development of targeted therapies or prevention strategies.

Stream 3 (Incubator): develop novel methods for using polygenic risk scores to identify subgroups of the population at high risk of common and complex diseases.

-Topic A: Cardiovascular disease

-Topic B: Diabetes

-Topic C: Other common and/or complex diseases

Stream 4 (Incubator): develop novel methods for improving accuracy and usefulness of polygenic risk scores to stratify people with common cancers for surveillance and treatment.

-Topic A: Breast Cancer

-Topic B: Colorectal cancer

-Topic C: Prostate cancer

-Topic D: Other common cancers

Stream 5 (TCR): undertake research to enhance or streamline uptake of clinical genomics into practice.

Stream 6 (Accelerator): develop and maintain infrastructure to support research collaboration by enabling data sharing, portability, longevity and connectivity of analysis across Australia. Research conducted should address emerging ethical, legal and social issues associated with the governance of clinical and genomic datasets with particular focus on the application of advanced analytics (e.g. AI) to enhance the diagnostic utility of genomics.

Applicants must propose research that addresses these objectives and those of the Genomics Health Futures Mission as outlined in the Roadmap and Implementation Plan.

This grant opportunity is being administered by NHMRC on behalf of the Australian Government Department of Health, Disability and Ageing. Further information on the MRFF is available here.

Applications will only be accepted from approved MRFF Eligible Organisations. A list of approved MRFF Eligible Organisations is available from the MRFF Eligible Organisations List on the NHMRC website. 

Applications must satisfy all the requirements set out in the Medical Research Future Fund – Genomics Health Futures Mission – 2026 Genomics Health Futures Grant Opportunity Guidelines. 

For Targeted Call for Research grants (Streams 1, 2 and 5): within 5 years from the commencement date specified in the grant schedule. 

For Incubator grants (Streams 3 and 4): within 2 years from the commencement date specified in the grant schedule. 

For Accelerator grants (Stream 6): within 5 years from the commencement date specified in the grant schedule.  

$74,000,000.00

From $0.00 to $8,000,000.00

Applicants are advised to read the Grant Guidelines thoroughly and liaise with the MRFF Eligible Organisation that will submit the application to identify any specific requirements that the Organisation might have. 

Applications must be submitted electronically using NHMRC’s online grant management system (Sapphire). 

Minimum data closes at 5:00pm (ACT Local Time) on 22 July 2026. 

Questions should be submitted no later than 1:00pm (ACT Local Time) on 12 August 2026.