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Grant Award View - GA143428

Molecular characterisation of the DBHS proteins in telomerase assembly

Contact Details

NHMRC Research Help Centre

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1800 500 983

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GA ID:
GA143428
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
26-Nov-2020
Publish Date:
21-Dec-2020
Category:
Health and Medical Research
Grant Term:
1-Jan-2021 to 31-Dec-2023
Value (AUD):
$686,246.00 (GST inclusive where applicable)

One-off/Ad hoc:
No
Aggregate Grant Award:
No

PBS Program Name:
NHMRC 19/20 1.1 Health and Medical Research
Grant Program:
Ideas
Grant Activity:
Molecular characterisation of the DBHS proteins in telomerase assembly
Purpose:
Telomerase is an enzyme that is active in over 90 percent of cancers. Telomerase activity allows cancer cells to divide an indefinite number of times. We have identified a novel role for the DBHS protein family in regulating telomerase activity. We aim to investigate the mechanisms by which these proteins function to assemble and transport telomerase to its site of action in the cell. We then aim to develop chemical inhibitors of these proteins, and test their utility in preventing cancer cell growth.

GO ID:
GO Title:
2020 Ideas Grants
Internal Reference ID:
GNT2003250
Selection Process:
Targeted or Restricted Competitive

Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property

Grant Recipient Details

Recipient Name:
University of Sydney
Recipient ABN:
15 211 513 464

Grant Recipient Location

Suburb:
Camperdown
Town/City:
Camperdown
Postcode:
2050
State/Territory:
NSW
Country:
AUSTRALIA

Grant Delivery Location

State/Territory:
NSW
Postcode:
Country:
AUSTRALIA

Contact Details

NHMRC Research Help Centre

:
1800 500 983

: