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Grant Award View - GA2574
A functional dissection of the bacterial replisome
GA ID:
GA2574
Agency:
Australian Research Council
Approval Date:
10-Nov-2017
Publish Date:
20-Feb-2018
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Jan-2018 to 31-Dec-2020
Value (AUD):
$524,298.00
(GST inclusive where applicable)
Variations:
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 17/18 Discovery
Grant Program:
Discovery Projects
Grant Activity:
A functional dissection of the bacterial replisome
Purpose:
This project aims to study the replisome, the machine that duplicates DNA before cell division. Years of biochemical research has shown how its protein components work, but observation at the single-molecule level is needed to understand how they all work together. This project aims to combine novel single-molecule biophysical tools with state-of-the-art biochemistry to define how the bacterial replisome coordinates synthesis of the two DNA strands and how it exchanges protein components on the fly. Expected outcomes of this project include improved understanding of a fundamental biological process, development of novel biophysical methodology, and training of the next generation of interdisciplinary scientists.
Internal Reference ID:
DP18 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
University of Wollongong
Recipient ABN:
61 060 567 686
Grant Recipient Location
Suburb:
WOLLONGONG
Town/City:
WOLLONGONG
Postcode:
2522
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
2522
Country:
AUSTRALIA