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Grant Award View - GA89314
Ataxia-telangiectasia: treating mitochondrial dysfunction with a novel...
GA ID:
GA89314
Agency:
Department of Health and Aged Care
Approval Date:
25-May-2020
Publish Date:
29-Jun-2020
Category:
Health and Medical Research
Grant Term:
1-Jun-2020 to 31-May-2023
Value (AUD):
$2,459,666.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
DoHAC 19/20 1.1 Health Policy Research and Analysis
Grant Program:
2019_MRFF_RCRDUN_RCRDUN_2020
Grant Activity:
Ataxia-telangiectasia: treating mitochondrial dysfunction with a novel form of anaplerosis
Purpose:
A-T is a rare genetic disease with ~ 40 known cases in Australia. They have neuro-degenerative disease, immune deficiency, and cancer, life expectancy is ~25years. There is no treatment for A-T. We have identified that altered calcium transport into mitochondria (cell batteries) leads to cell death, that treating A-T cells with Triheptanoin (C7) corrects these defects. C7 has been used safely for 15 years in other metabolic diseases. We intend to conduct a trial of C7 in A-T patients.
GO ID:
GO Title:
MRFF Clinical Trials Activity - RCRDUN Initiative – 2019 Rare Cancers, Rare Diseases and Unmet Need Grant Opportunity
Internal Reference ID:
MRF1200255
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of Queensland
Recipient ABN:
63 942 912 684
Grant Recipient Location
Suburb:
St Lucia
Town/City:
St Lucia
Postcode:
4072
State/Territory:
QLD
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
QLD
Postcode:
Country:
AUSTRALIA