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Grant Award View - GA206699
Type 2 diabetes relief by UPR-mediated beta cell protection
GA ID:
GA206699
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
3-Nov-2021
Publish Date:
20-Dec-2021
Category:
Medical Research
Grant Term:
1-Jan-2022 to 31-Dec-2025
Value (AUD):
$1,000,959.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 20/21 1.1 Health and Medical Research
Grant Program:
Ideas Grants
Grant Activity:
Type 2 diabetes relief by UPR-mediated beta cell protection
Purpose:
Type 2 diabetes (T2D) is caused by insulin deficiency, with obesity a strong risk factor. However, only a small fraction of obese individuals develops T2D. Usually the pancreatic β-cells increase insulin release. This proposal will test the novel hypothesis that an adaptive response to stress helps β-cells increase insulin release and protect against T2D by preventing the conversion of β-cells to other pancreatic cell types. The studies are important for the development of novel therapy for T2D.
GO ID:
GO Title:
2021 Ideas Grants
Internal Reference ID:
2021/GNT2012142
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of New South Wales
Recipient ABN:
57 195 873 179
Grant Recipient Location
Suburb:
Sydney
Town/City:
Sydney
Postcode:
2052
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
ACT, NSW
Postcode:
Multiple
Country:
AUSTRALIA