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Grant Award View - GA215379
Using venoms to map critical and evolutionary conserved vulnerabilities
GA ID:
GA215379
Agency:
Australian Research Council
Approval Date:
19-Jan-2022
Publish Date:
25-Jan-2022
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
15-Mar-2022 to 14-Mar-2025
Original: 19-Jan-2022 to 31-Dec-2024
Value (AUD):
$528,000.00
(GST inclusive where applicable)
Variations:
- GA215379-V1 - Variation to Grant (21-Apr-2022 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 21/22 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Using venoms to map critical and evolutionary conserved vulnerabilities
Purpose:
We have developed and applied new functional genomic approaches to study venom evolution. Using CRISPR screening, we find that unrelated venoms act on cells by exploiting the same vulnerabilities. By functionally mapping these vulnerabilities for all venom classes, we can begin to develop universal venom antidotes. Conversely, much of what we know about venom mechanisms comes from a small percentage of the biodiversity within a venom, and we have developed genomic tools to study the venom “dark matterâ€. This work will lead to the full molecular characterisation of venom biodiversity, and new venom components will be useful for research or as novel medicines.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2022
Internal Reference ID:
DP22 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Sydney
Recipient ABN:
15 211 513 464
Grant Recipient Location
Suburb:
FOREST LODGE
Town/City:
FOREST LODGE
Postcode:
2037
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
2037
Country:
AUSTRALIA