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Grant Award View - GA64689-V4
Revealing molecular detail of DNA triplexes to underpin antigene...
GA ID:
GA64689-V4
Agency:
Australian Research Council
Approval Date:
4-Dec-2019
Variation Publish Date:
6-Jul-2023
Variation Date:
4-Jul-2023
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Jul-2020 to 29-Jun-2024
Value (AUD):
$450,000.00
(GST inclusive where applicable)
Varies:
GA64689
- Revealing molecular detail of DNA triplexes to underpin antigene technology
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 19/20 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Revealing molecular detail of DNA triplexes to underpin antigene technology
Purpose:
Variations from the classic DNA double helix structure are proposed to play key roles in a range of cellular processes, particularly gene regulation. However, the biological function and therapeutic potential of these unusual DNA structures are poorly explored, since the fundamental molecular details which govern their formation and interactions with cellular machinery are not well described. This project aims to develop innovative methods to investigate, and importantly modulate, DNA and RNA triple helix assembly, specificity and molecular interactions. Resulting insights will underpin novel approaches to gene regulation, principally in the context of designing new antibacterial agents to address the antibacterial resistance problem.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2020
Internal Reference ID:
DP20 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Adelaide
Recipient ABN:
61 249 878 937
Grant Recipient Location
Suburb:
ADELAIDE
Town/City:
ADELAIDE
Postcode:
5000
State/Territory:
SA
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
SA
Postcode:
5000
Country:
AUSTRALIA