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Grant Award View - GA120002
Tracking DNA repair dynamics in the nuclear landscape of a living cell
GA ID:
GA120002
Agency:
Australian Research Council
Approval Date:
26-Aug-2020
Publish Date:
1-Sep-2020
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Apr-2021 to 31-Mar-2025
Original: 26-Aug-2020 to 30-Jun-2024
Value (AUD):
$876,000.00
(GST inclusive where applicable)
Variations:
- GA120002-V3 - Variation to Grant (20-Oct-2021 )
- GA120002-V2 - Variation to Grant (2-Aug-2021 )
- GA120002-V1 - Variation to Grant (30-Mar-2021 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 20/21 Discovery
Grant Program:
ARC Future Fellowships
Grant Activity:
Tracking DNA repair dynamics in the nuclear landscape of a living cell
Purpose:
This project aims to track DNA repair factor recruitment in the nuclear landscape of a living cell and quantify the role of nucleus architecture in maintenance of genome integrity. By coupling advanced fluorescence microscopy with a novel DNA double strand break inducible cell system, this project expects to uncover how the nucleus spatially coordinates DNA damage detection, assessment and repair in real time. This research is important because DNA damage threatens organism survival and this project has the potential to define how this genomic threat is resolved at the single molecule level. The benefit of this research is a fundamental insight into DNA repair biology and development of imaging technology to quantify genome function.
GO ID:
GO Title:
Future Fellowships for funding commencing in 2020
Internal Reference ID:
FT20 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Melbourne
Recipient ABN:
84 002 705 224
Grant Recipient Location
Suburb:
UNIVERSITY OF MELBOURNE
Town/City:
UNIVERSITY OF MELBOURNE
Postcode:
3010
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
3010
Country:
AUSTRALIA