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Grant Award View - GA204240
Elucidating the function of host-derived cysteine in bacterial virulence
GA ID:
GA204240
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
3-Nov-2021
Publish Date:
6-Dec-2021
Category:
Medical Research
Grant Term:
1-Jan-2022 to 1-Jan-2025
Value (AUD):
$300,922.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 20/21 1.1 Health and Medical Research
Grant Program:
Ideas Grants
Grant Activity:
Elucidating the function of host-derived cysteine in bacterial virulence
Purpose:
Our immune system responds to stomach infection with Helicobacter pylori by producing high levels of defence molecules called reactive oxygen species (ROS). However, H. pylori can withstand ROS, and they fail to clear the infection, but in the long term, ROS damage the stomach lining resulting in disease. This project tests the hypothesis that H. pylori uses amino acids cysteine and cystine available in the stomach lining to combat ROS. The outcomes will aid future design of new antimicrobials.
GO ID:
GO Title:
2021 Ideas Grants
Internal Reference ID:
2021/GNT2011010
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
Clayton
Town/City:
Clayton
Postcode:
3800
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
ACT, VIC
Postcode:
Multiple
Country:
AUSTRALIA