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Grant Award View - GA143620
Unravelling NET confusion in Vasculitis
GA ID:
GA143620
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
26-Nov-2020
Publish Date:
21-Dec-2020
Category:
Health and Medical Research
Grant Term:
1-Jan-2021 to 31-Dec-2024
Value (AUD):
$1,044,052.30
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 19/20 1.1 Health and Medical Research
Grant Program:
Ideas
Grant Activity:
Unravelling NET confusion in Vasculitis
Purpose:
Current therapy for AAV has major toxicities and 30 percent of Patients are dead or on dialysis within 3 years. This proposal aims to study a unique form of cell death termed Neutrophil extracellular traps (NETs) that initiates and perpetuates inflammation in this disease. We will use an animal model of the disease that mirrors human disease. We will inhibit crucial molecules in NET production to attenuate disease. This will provide proof of concept evidence to promote clinical trials in patients.
GO ID:
GO Title:
2020 Ideas Grants
Internal Reference ID:
GNT2001325
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
Clayton
Town/City:
Clayton
Postcode:
3800
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC, QLD, Overseas
Postcode:
Multiple
Country:
AUSTRALIA, SWEDEN