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Grant Award View - GA2587-V1
Molecular Interactions with an antibiotic target in DNA replication
GA ID:
GA2587-V1
Agency:
Australian Research Council
Approval Date:
10-Nov-2017
Variation Publish Date:
11-May-2021
Variation Date:
11-May-2021
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Jan-2018 to 7-Feb-2021
Value (AUD):
$534,573.00
(GST inclusive where applicable)
Varies:
GA2587
- Molecular Interactions with an antibiotic target in DNA replication
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 17/18 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Molecular Interactions with an antibiotic target in DNA replication
Purpose:
This project aims to develop and use new technologies to address mechanistic aspects of anti-bacterial compounds in development, and of the development of resistance to them. The project will focus on the sliding clamp subunit of the bacterial replicative polymerase by studying its association with many other proteins in vitro and in vivo, using novel techniques in solid-state NMR, single-molecule fluorescence and molecular microbiology. The outcomes are expected to be an increased understanding of bacterial DNA replication and mechanisms of antibiotic action and resistance. This project expects to generate new knowledge to assist in combatting antibiotic resistance in Gram-negative bacterial pathogens.
Internal Reference ID:
DP18 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
University of Wollongong
Recipient ABN:
61 060 567 686
Grant Recipient Location
Suburb:
WOLLONGONG
Town/City:
WOLLONGONG
Postcode:
2522
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
2522
Country:
AUSTRALIA