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Grant Award View - GA142432
Probing the role of dynamics in protein modulation of GPCR phenotype
GA ID:
GA142432
Agency:
Australian Research Council
Approval Date:
11-Dec-2020
Publish Date:
15-Dec-2020
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Jun-2021 to 31-Dec-2023
Original: 1-Jan-2021 to 31-Dec-2023
Value (AUD):
$645,189.89
(GST inclusive where applicable)
Original:
$645,190.00
Variations:
- GA142432-V5 - Variation to Grant (17-Apr-2024 )
- GA142432-V4 - Variation to Grant (3-May-2023 )
- GA142432-V3 - Variation to Grant (21-Jun-2022 )
- GA142432-V2 - Variation to Grant (20-Oct-2021 )
- GA142432-V1 - Variation to Grant (2-Aug-2021 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 20/21 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Probing the role of dynamics in protein modulation of GPCR phenotype
Purpose:
Life relies upon the fundamental ability to convert external stimuli into an appropriate biological response. Such stimuli are transmitted by cell surface proteins (receptors), which convert this stimulus into an intracellular signal. The largest group of cell surface receptors is the G protein-coupled receptor (GPCR) family. Despite advances in GPCR structure determination, many questions regarding the structural basis of GPCR function and signalling remain unanswered. The primary outcome of this project is to provide mechanistic insight into the dynamics of GPCR ligand recognition and activation to advance our understanding of GPCR signal transduction, a fundamental biological process for all living organisms.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2021
Internal Reference ID:
DP21 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
CLAYTON
Town/City:
CLAYTON
Postcode:
3168
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
3168
Country:
AUSTRALIA