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Grant Award View - GA29114-V1
Phosphoinositide regulation of lysosome reformation during autophagy
GA ID:
GA29114-V1
Agency:
Australian Research Council
Approval Date:
27-Nov-2018
Variation Publish Date:
7-Aug-2020
Variation Date:
7-Aug-2020
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
18-Mar-2019 to 17-Mar-2022
Value (AUD):
$475,000.00
(GST inclusive where applicable)
Varies:
GA29114
- Phosphoinositide regulation of lysosome reformation during autophagy
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 18/19 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Phosphoinositide regulation of lysosome reformation during autophagy
Purpose:
This project aims to investigate a new critical step in the autophagy pathway, autophagic lysosome reformation, a fundamental, evolutionarily conserved mechanism for cellular homeostasis. By combining gene function studies with advanced cellular imaging techniques, this project will investigate the dynamic membrane changes that drive this lysosome recycling pathway and how it is regulated by a hierarchical succession of specific enzymes. The expected outcome will be to re-define the archetypical autophagy pathway and characterise novel mechanisms by which it is controlled. This project will reveal new fundamental biological processes, and act as a framework for developing new imaging modalities and tools for studying autophagy.
GO ID:
GO Title:
Discovery Projects commencing in 2019
Internal Reference ID:
DP19 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
MULGRAVE
Town/City:
MULGRAVE
Postcode:
3170
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
3170
Country:
AUSTRALIA