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Grant Award View - GA166526
Repurposing valproate for the treatment of colorectal cancer
GA ID:
GA166526
Agency:
Department of Health and Aged Care
Approval Date:
7-May-2021
Publish Date:
25-May-2021
Category:
Health and Medical Research
Grant Term:
1-Jun-2021 to 31-May-2024
Value (AUD):
$751,884.70
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
DoHAC 20/21 1.1 Health Policy Research and Analysis
Grant Program:
2020_MRFF_Efficient_Use_of_Existing_Medicines
Grant Activity:
Repurposing valproate for the treatment of colorectal cancer
Purpose:
Colorectal cancer is a major cause of cancer related deaths for which there is an urgent need to develop new treatments. The drug valproate has been used to treat epilepsy and mood disorders for over 50 years. We have found that valproate can profoundly increase the anti-tumour activity of a class of drugs known as EGFR inhibitors in laboratory models of colon cancer. We will now test the activity of this drug combination in a phase II clinical trial in patients with advanced colon cancer.
GO ID:
GO Title:
MRFF – PPHR Initiative – 2020 Efficient Use of Existing Medicines Grant Opportunity
Internal Reference ID:
MRF2007450
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
La Trobe University
Recipient ABN:
64 804 735 113
Grant Recipient Location
Suburb:
Bundoora
Town/City:
Bundoora
Postcode:
3083
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW, VIC, SA, QLD
Postcode:
Multiple
Country:
AUSTRALIA