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Grant Award View - GA85509

Investigating the atomic structure of an immune cell inhibitory receptor

Contact Details

ARC NCGP General Enquiries

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02 6287 6600

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GA ID:
GA85509
Agency:
Australian Research Council
Approval Date:
19-Jun-2020
Publish Date:
23-Jun-2020
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
27-Aug-2020 to 31-Dec-2023
Original: 1-Jul-2020 to 30-Jun-2023
Value (AUD):
$671,427.00 (GST inclusive where applicable)
Variations:
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 19/20 Linkage
Grant Program:
Linkage Projects
Grant Activity:
Investigating the atomic structure of an immune cell inhibitory receptor
Purpose:
T cells play a key role in the adaptive immune system, whose reactivity must be controlled to prevent aberrant reactivity. Central to the function of T cells is the T cell antigen receptor, and a host of co-stimulatory molecules, co-receptors and inhibitory receptors. This proposal, in partnership with Immutep Ltd, aims to gain a basic understanding of the structure and function of a key inhibitory receptor found on T cells, termed the Lymphocyte activation gene-3 (LAG-3). The proposal utilises a combination of cellular immunology and structural biology to gain insight into the form and function of the LAG-3 molecule. Ultimately this fundamental knowledge can be used by the biotechnology industry.
GO ID:
GO2093
GO Title:
Linkage Projects for funding applied for in 2019
Internal Reference ID:
LP19 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No

Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012

Grant Recipient Location
Suburb:
CLAYTON
Town/City:
CLAYTON
Postcode:
3168
State/Territory:
VIC
Country:
AUSTRALIA

Grant Delivery Location
State/Territory:
VIC
Postcode:
3168
Country:
AUSTRALIA

Contact Details

ARC NCGP General Enquiries

:
02 6287 6600

: