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Grant Award View - GA68449
The T cell genome in 3D: linking chromatin structure to cellular...
GA ID:
GA68449
Agency:
Australian Research Council
Approval Date:
20-Dec-2019
Publish Date:
6-Jan-2020
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Jun-2020 to 1-Jun-2024
Original: 1-Jan-2020 to 31-Dec-2022
Value (AUD):
$705,000.00
(GST inclusive where applicable)
Variations:
- GA68449-V4 - Variation to Grant (21-Jun-2022 )
- GA68449-V3 - Variation to Grant (20-Oct-2021 )
- GA68449-V2 - Variation to Grant (2-Aug-2021 )
- GA68449-V1 - Variation to Grant (1-Jun-2021 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 19/20 Discovery
Grant Program:
Discovery Projects
Grant Activity:
The T cell genome in 3D: linking chromatin structure to cellular function
Purpose:
Adaptive immune cell activation results in the acquisition and long term maintenance of specific cellular function that enables efficient immune control of infections. Using advanced cellular and genomic approaches, combined with high-resolution microscopy and cutting edge computational biology, this proposal aims to address major gaps in our knowledge about how alterations in genomic 3D architecture and targeted biochemical modifications impact cell specific gene nuclear positioning and how this regulates changes in gene expression associated with immune cell activation. An outcome will be identification of novel molecular mechanisms that will have broad applicability across cellular biology, and provide novel targets for drug development.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2020
Internal Reference ID:
DP20 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
MULGRAVE
Town/City:
MULGRAVE
Postcode:
3170
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
3170
Country:
AUSTRALIA