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Grant Award View - GA68345
The “New†Biochemistry of Polyamines: When Metabolic Pathways...
GA ID:
GA68345
Agency:
Australian Research Council
Approval Date:
19-Dec-2019
Publish Date:
6-Jan-2020
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
17-Aug-2020 to 16-Aug-2023
Original: 1-Jan-2020 to 31-Dec-2022
Value (AUD):
$437,420.00
(GST inclusive where applicable)
Variations:
- GA68345-V4 - Variation to Grant (20-Oct-2021 )
- GA68345-V3 - Variation to Grant (2-Aug-2021 )
- GA68345-V2 - Variation to Grant (28-Apr-2021 )
- GA68345-V1 - Variation to Grant (19-May-2020 )
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 19/20 Discovery
Grant Program:
Discovery Projects
Grant Activity:
The “New†Biochemistry of Polyamines: When Metabolic Pathways Collide
Purpose:
Basic biochemistry and the metabolic regulation of proliferation remain as the fundamental building blocks of knowledge in cell biology that have enabled breakthrough advances in biology and medicine. Polyamines are unique and ubiquitous low-Mr amines that play vital roles in many biological processes, including proliferation, DNA/RNA synthesis, etc. This proposal will mechanistically dissect the "new" biochemistry of polyamines, as we have discovered that polyamines are regulated by iron at 2-major levels, involving >10-key polyamine pathway proteins. This proposal represents first-in-field studies specifically designed to dissect mechanisms involved in this relationship. Our Central Hypothesis is that iron regulates polyamine metabolism.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2020
Internal Reference ID:
DP20 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
Griffith University
Original: The University of Sydney
Recipient ABN:
78 106 094 461
Original:
15 211 513 464
Grant Recipient Location
Suburb:
SOUTHPORT
Town/City:
SOUTHPORT
Postcode:
4222
State/Territory:
QLD
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
QLD
Postcode:
4222
Country:
AUSTRALIA