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Grant Award View - GA204254
The role of Piezo1 and TRPM4 ion channels in pathophysiology of cardiac...
GA ID:
GA204254
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
3-Nov-2021
Publish Date:
6-Dec-2021
Category:
Medical Research
Grant Term:
1-Jan-2022 to 31-Dec-2026
Value (AUD):
$1,207,705.25
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 20/21 1.1 Health and Medical Research
Grant Program:
Ideas Grants
Grant Activity:
The role of Piezo1 and TRPM4 ion channels in pathophysiology of cardiac mechano-electric coupling
Purpose:
Heart hypertrophy is an important risk factor for premature death from a heart disease. In this project we propose to study a new cellular signalling pathway causing heart hypertrophy due to systemic increase in blood pressure. The biological molecules central to this new cellular pathway are the Piezo1 and TRPM4 ion channels underlying contractions of the heart muscle. This project aims to establish a novel paradigm in our understanding of the molecular origins of heart hypertrophy.
GO ID:
GO Title:
2021 Ideas Grants
Internal Reference ID:
2021/GNT2010464
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of New South Wales
Recipient ABN:
57 195 873 179
Grant Recipient Location
Suburb:
Sydney
Town/City:
Sydney
Postcode:
2052
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
ACT, NSW
Postcode:
Multiple
Country:
AUSTRALIA