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Grant Award View - GA276560
Harnessing a native corticosteroid-binding globulin to treat...
GA ID:
GA276560
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
27-Oct-2022
Publish Date:
19-Dec-2022
Category:
Medical Research
Grant Term:
1-Jan-2023 to 31-Dec-2026
Value (AUD):
$1,235,442.20
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 21/22 1.1 Health and Medical Research
Grant Program:
Ideas Grants
Grant Activity:
Harnessing a native corticosteroid-binding globulin to treat life-threatening septic shock
Purpose:
Septic shock is a maladaptive response to overwhelming infection that leads to organ failure and death. Corticosteroid-binding globulin (CBG) is a blood protein with unique properties to deliver the body’s natural anti-inflammatory hormone, glucocorticoid, to threatened organs - but its excessive depletion in septic shock triples the risk of dying. Our experiments in mouse models of sepsis are important next steps towards the use of CGB therapy to prevent deterioration and death in patients.
GO ID:
GO Title:
Ideas Grants 2022
Internal Reference ID:
2022/GNT2019948
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
The University of Adelaide
Recipient ABN:
61 249 878 937
Grant Recipient Location
Suburb:
Adelaide
Town/City:
Adelaide
Postcode:
5000
State/Territory:
SA
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
ACT, SA
Postcode:
Multiple
Country:
AUSTRALIA