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Grant Award View - GA1008
Modulation of endothelial junctions as selective immunotherapy
GA ID:
GA1008
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
24-Oct-2017
Publish Date:
30-Jan-2018
Category:
Medical Research
Grant Term:
1-Jan-2018 to 31-Dec-2020
Value (AUD):
$924,146.31
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 16/17 1.1 Health and Medical Research
Grant Program:
Project
Grant Activity:
Modulation of endothelial junctions as selective immunotherapy
Purpose:
We have developed a new drug (CD5-2) that targets the junctions of endothelial cells, the cell that lines all vessels. CD5-2 reduces oedema in diseases such as diabetic retinopathy and tumours. Thus it has potential as a new therapeutic in chronic inflammatory diseases where leaky blood vessels are central to the pathology. This grant will provide fundamental understanding of how CD5-2 induces such profound effects to alter the levels of oedema and alter inflammatory cell infiltrates in tissues.
Internal Reference ID:
GNT1143230
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of Sydney
Recipient ABN:
15 211 513 464
Grant Recipient Location
Suburb:
Camperdown
Town/City:
Camperdown
Postcode:
2050
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
Country:
AUSTRALIA