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Grant Award View - GA995
Uncovering new epigenetic-based regulatory mechanisms of gene...
GA ID:
GA995
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
24-Oct-2017
Publish Date:
30-Jan-2018
Category:
Medical Research
Grant Term:
1-Jan-2018 to 31-Dec-2021
Value (AUD):
$1,068,422.10
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 16/17 1.1 Health and Medical Research
Grant Program:
Project
Grant Activity:
Uncovering new epigenetic-based regulatory mechanisms of gene expression: novel links between histone variants, RNA function and disease
Purpose:
It is estimated that greater than 90 percent of human genes undergo alternative RNA splicing, which can explain how protein diversity is achieved with a limited number of genes. However, how alternative splicing patterns are established remains poorly understood but is an important question given that 15-50 percent of human disease mutations are associated with changes to the splicing patterns of RNA. We have uncovered a new splicing mechanism, which involves changing the way DNA is packaged in a cell.
Internal Reference ID:
GNT1142399
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Australian National University
Recipient ABN:
52 234 063 906
Grant Recipient Location
Suburb:
Canberra City
Town/City:
Canberra City
Postcode:
2601
State/Territory:
ACT
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
ACT
Postcode:
Country:
AUSTRALIA