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Grant Award View - GA147119
Understanding the role of DNMT1 SUMOylation in Acute Myeloid Leukaemia
GA ID:
GA147119
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
26-Nov-2020
Publish Date:
18-Jan-2021
Category:
Health and Medical Research
Grant Term:
1-Jan-2021 to 31-Dec-2023
Value (AUD):
$648,240.05
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 19/20 1.1 Health and Medical Research
Grant Program:
Ideas
Grant Activity:
Understanding the role of DNMT1 SUMOylation in Acute Myeloid Leukaemia
Purpose:
Most cancers have abnormally high levels of DNA methylation, which turns off cell death genes, making cancer cells immortal. We have a new drug, called DNMT1i, that targets this feature of cancer cells and we recently found a new drug target that enhances the activity of DNMT1i. Our research will determine how these two drugs synergise to effectively kill cancer cells and will justify their use in clinical trials, which we believe will improve outcomes for patients with cancer.
GO ID:
GO Title:
2020 Ideas Grants
Internal Reference ID:
GNT2003909
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of Melbourne
Recipient ABN:
84 002 705 224
Grant Recipient Location
Suburb:
Parkville
Town/City:
Parkville
Postcode:
3052
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
Country:
AUSTRALIA