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Grant Award View - GA217922
Accelerating clot lysis in ischemic stroke with dornase alfa in an...
GA ID:
GA217922
Agency:
Department of Health and Aged Care
Approval Date:
6-Dec-2021
Publish Date:
16-Feb-2022
Category:
Health and Medical Research
Grant Term:
1-Feb-2022 to 31-Jan-2026
Value (AUD):
$1,453,336.70
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
DoHAC 21/22 1.1 Health Policy Research and Analysis
Grant Program:
MRFF Research Grants
Grant Activity:
Accelerating clot lysis in ischemic stroke with dornase alfa in an Umbrella Bayesian Optimised Phase 2 trial
Purpose:
Stroke remains a major cause of disability. Clot-dissolving medicines targeting fibrin can be rapidly delivered at most Australian hospitals. DNA extruded by white blood cells is another key structural component of clot. Dornase, an approved medicine for other diseases, dissolves DNA and we showed accelerated clot dissolving when combined with standard treatment. Our trial will test whether dornase can accelerate restoration of blood flow to improve outcomes in up to 300 patients with stroke.
GO ID:
GO Title:
MRFF 2021 Rare Cancers Rare Diseases Unmet Need General - Grant Opportunity
Internal Reference ID:
2021/MRF2014406
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of Melbourne
Recipient ABN:
84 002 705 224
Grant Recipient Location
Suburb:
Parkville
Town/City:
Parkville
Postcode:
3052
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
Country:
AUSTRALIA