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Grant Award View - GA206688
The mesenchymal stromal cell paradox – living cell therapy or dying...
GA ID:
GA206688
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
3-Nov-2021
Publish Date:
20-Dec-2021
Category:
Medical Research
Grant Term:
1-Jan-2022 to 1-Jan-2025
Value (AUD):
$957,031.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 20/21 1.1 Health and Medical Research
Grant Program:
Ideas Grants
Grant Activity:
The mesenchymal stromal cell paradox – living cell therapy or dying therapeutic cell?
Purpose:
Mesenchymal stromal cells (MSCs) can dampen inflammation and aid tissue repair, but efforts to improve their clinical utility are hampered by our poor understanding of how they work. We have found that the therapeutic effects of MSCs depend on their cell death, which triggers immune suppression. Instead of focussing on viable MSCs, we will investigate how dying MSCs modify immune responses. Our discoveries will enable more effective cell therapies for a wide range of diseases.
GO ID:
GO Title:
2021 Ideas Grants
Internal Reference ID:
2021/GNT2012290
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
Clayton
Town/City:
Clayton
Postcode:
3800
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
ACT, VIC
Postcode:
Multiple
Country:
AUSTRALIA