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Grant Award View - GA143573
A novel, actionable pathway promoting metastasis of triple negative...
GA ID:
GA143573
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
26-Nov-2020
Publish Date:
21-Dec-2020
Category:
Health and Medical Research
Grant Term:
1-Jan-2021 to 31-Dec-2023
Value (AUD):
$708,272.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 19/20 1.1 Health and Medical Research
Grant Program:
Ideas
Grant Activity:
A novel, actionable pathway promoting metastasis of triple negative breast cancer
Purpose:
Triple negative breast cancer (TNBC) is particularly aggressive and lacks targeted therapies, limiting treatment to chemotherapy. A protein termed PEAK1 drives TNBC but has remained 'undruggable'. Recently, we identified an enzyme, termed CAMK2D, that acts downstream of PEAK1 and mediates its effects. In this grant we will characterize the mechanism of CAMK2D and determine the effect of a drug that blocks its action. This may lead to a new targeted and personalized treatment for TNBC.
GO ID:
GO Title:
2020 Ideas Grants
Internal Reference ID:
GNT2003599
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
Clayton
Town/City:
Clayton
Postcode:
3800
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
Country:
AUSTRALIA