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Grant Award View - GA206660
Identifying rational approaches to enhance the activity of BH3 mimetic...
GA ID:
GA206660
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
3-Nov-2021
Publish Date:
20-Dec-2021
Category:
Medical Research
Grant Term:
1-Jan-2022 to 31-Dec-2023
Value (AUD):
$1,091,535.94
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 20/21 1.1 Health and Medical Research
Grant Program:
Ideas Grants
Grant Activity:
Identifying rational approaches to enhance the activity of BH3 mimetic drugs in blood cancers
Purpose:
It is now appreciated that normal cell death prevents cancers from developing; however, this could be undermined in blood cancers (e.g., leukemias). This is often due to overactivity of BCL2 which allows the cancer cells to persist. Treating patients with a drug blocking BCL2 - venetoclax - is proving highly effective for such blood cancers. However, the disease will often eventually recur: this project seeks to understand why this is and to discover ways by which this can be prevented.
GO ID:
GO Title:
2021 Ideas Grants
Internal Reference ID:
2021/GNT2013478
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
The Walter and Eliza Hall Institute of Medical Research
Recipient ABN:
12 004 251 423
Grant Recipient Location
Suburb:
Parkville
Town/City:
Parkville
Postcode:
3052
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
ACT, VIC
Postcode:
Multiple
Country:
AUSTRALIA