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Grant Award View - GA68377-V2
Conotoxin diversification and evolution of venom peptides in cone snails
GA ID:
GA68377-V2
Agency:
Australian Research Council
Approval Date:
20-Dec-2019
Variation Publish Date:
20-Oct-2021
Variation Date:
12-Oct-2021
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Jan-2020 to 31-Dec-2022
Value (AUD):
$540,000.00
(GST inclusive where applicable)
Varies:
GA68377
- Conotoxin diversification and evolution of venom peptides in cone snails
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 19/20 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Conotoxin diversification and evolution of venom peptides in cone snails
Purpose:
The marine snails of the genus Conus have evolved one of the most complex venoms that has emerged as a rich source of novel bioactive peptides. However, < 0.1% of their true potential has been characterised to-date. Using advanced genomic, proteomic, structural and pharmacological approaches pioneered in our laboratory, this study will decipher how conotoxin diversification from ancestral worm hunters facilitated the shift in diet to modern fish and mollusc hunting species by determining the evolutionary trajectories of positively selected conotoxins. Investigation of the structure and function of these highly optimised venom peptides will provide new research tools and potential leads to new pharmaceuticals and agrochemicals.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2020
Internal Reference ID:
DP20 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Queensland
Recipient ABN:
63 942 912 684
Grant Recipient Location
Suburb:
ST LUCIA
Town/City:
ST LUCIA
Postcode:
4067
State/Territory:
QLD
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
QLD
Postcode:
4067
Country:
AUSTRALIA