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Grant Award View - GA66029
Proinsulin sorting at the trans-Golgi-network.
GA ID:
GA66029
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
12-Nov-2019
Publish Date:
16-Dec-2019
Category:
Health and Medical Research
Grant Term:
1-Jan-2020 to 31-Dec-2022
Value (AUD):
$601,672.50
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 18/19 1.1 Health and Medical Research
Grant Program:
Ideas
Grant Activity:
Proinsulin sorting at the trans-Golgi-network.
Purpose:
A major feature in the pathogenesis of type 2 diabetes is the loss of pancreatic ?-cell function characterised by reduced glucose-induced insulin secretion and increased secretion of unprocessed proinsulin. This may be due to defects in proinsulin sorting into secretory vesicles and processing of proinsulin into insulin. The exact mechanisms that are responsible for sorting of proinsulin into vesicles are not fully defined. Our aim is to discover key proteins and steps involved in this process.
GO ID:
GO Title:
Ideas Grants 2019
Internal Reference ID:
GNT1184874
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of Sydney
Recipient ABN:
15 211 513 464
Grant Recipient Location
Suburb:
Camperdown
Town/City:
Camperdown
Postcode:
2050
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW, Overseas
Postcode:
Multiple
Country:
AUSTRALIA, UNITED STATES