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Grant Award View - GA65989
Opening the black box - studies of the major histocompatibility complex...
GA ID:
GA65989
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
12-Nov-2019
Publish Date:
16-Dec-2019
Category:
Health and Medical Research
Grant Term:
1-Jan-2020 to 31-Dec-2024
Value (AUD):
$2,491,346.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 18/19 1.1 Health and Medical Research
Grant Program:
Ideas
Grant Activity:
Opening the black box - studies of the major histocompatibility complex class I immunopeptidome in allorecognition and transplant tolerance induction
Purpose:
Transplant patients require immunosuppression to prevent rejection; this carries serious side effects. Training the immune system to accept the transplant (tolerance) would improve outcomes. The recipient’s T cells recognise protein fragments (peptides) together with the donor’s transplant antigens. The project will identify these peptides, and the T cell receptors which bind them, and use this knowledge to monitor transplant immune responses and to improve strategies for tolerance induction.
GO ID:
GO Title:
Ideas Grants 2019
Internal Reference ID:
GNT1183806
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of Sydney
Recipient ABN:
15 211 513 464
Grant Recipient Location
Suburb:
Camperdown
Town/City:
Camperdown
Postcode:
2050
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW, VIC
Postcode:
Multiple
Country:
AUSTRALIA