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Grant Award View - GA65869

Why do we have SARM 1 protein if knocking it out prevents axons...

Contact Details

NHMRC Research Help Centre

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1800 500 983

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GA ID:
GA65869
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
12-Nov-2019
Publish Date:
16-Dec-2019
Category:
Health and Medical Research
Grant Term:
1-Jan-2020 to 31-Dec-2022
Value (AUD):
$597,651.00 (GST inclusive where applicable)

One-off/Ad hoc:
No
Aggregate Grant Award:
No

PBS Program Name:
NHMRC 18/19 1.1 Health and Medical Research
Grant Program:
Ideas
Grant Activity:
Why do we have SARM 1 protein if knocking it out prevents axons degenerating?
Purpose:
Nerve cells communicate through messages sent along axons. Axon loss in neurodegenerative disease prevents communication, resulting in symptoms such as loss of movement or memory. We will investigate whether the nervous systems programmed axon removal pathways are abnormally activated in disease or whether they function to protect the nervous system from in-proper function. This will have consequences for our treatment of neurodegenerative diseases such as dementia and motor-neuron disease.

GO ID:
GO Title:
Ideas Grants 2019
Internal Reference ID:
GNT1187156
Selection Process:
Targeted or Restricted Competitive

Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property

Grant Recipient Details

Recipient Name:
University of Tasmania
Recipient ABN:
30 764 374 782

Grant Recipient Location

Suburb:
Hobart
Town/City:
Hobart
Postcode:
7000
State/Territory:
TAS
Country:
AUSTRALIA

Grant Delivery Location

State/Territory:
TAS
Postcode:
Country:
AUSTRALIA

Contact Details

NHMRC Research Help Centre

:
1800 500 983

: