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Grant Award View - GA65857
The clock as a therapeutic target to improve sleep quality and circadian...
GA ID:
GA65857
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
12-Nov-2019
Publish Date:
16-Dec-2019
Category:
Health and Medical Research
Grant Term:
1-Jan-2020 to 31-Dec-2023
Value (AUD):
$890,837.50
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 18/19 1.1 Health and Medical Research
Grant Program:
Ideas
Grant Activity:
The clock as a therapeutic target to improve sleep quality and circadian dysfunction in Parkinson’s disease: fighting neurodegeneration by treating chronodegeneration.
Purpose:
We propose a novel approach to slow or prevent the progression of Parkinson’s disease (PD) - by change of circadian and sleeping patterns with a drug targeting the regulator (Per1) of our internal clock. We hypothesize that blocking or reducing Per1 will improve sleep quality and restore healthy circadian rhythms which are dysregulated in PD. As a consequence, we expect to see reduced motor and non-motor symptoms which are known to occur in PD due to disruptions of sleep and biological rhythms.
GO ID:
GO Title:
Ideas Grants 2019
Internal Reference ID:
GNT1186943
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of Queensland
Recipient ABN:
63 942 912 684
Grant Recipient Location
Suburb:
St Lucia
Town/City:
St Lucia
Postcode:
4072
State/Territory:
QLD
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
QLD
Postcode:
Country:
AUSTRALIA