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Grant Award View - GA65833
Cell competition as a tumour suppressor mechanism in leukaemia
GA ID:
GA65833
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
12-Nov-2019
Publish Date:
16-Dec-2019
Category:
Health and Medical Research
Grant Term:
1-Jan-2020 to 31-Dec-2022
Value (AUD):
$577,282.20
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 18/19 1.1 Health and Medical Research
Grant Program:
Ideas
Grant Activity:
Cell competition as a tumour suppressor mechanism in leukaemia
Purpose:
Using a model of T cell pre-leukemia, we have seen that cells in the thymus engage in cell competition and that this is important for preventing cancer. We have shown that a particular gene is critical for this competition. We have discovered that this gene plays a role in normal and pre-malignant blood stem cells in the marrow. We aim to show the function of this gene is to maintain blood stem cell health, and prevent leukaemia, via a cell competition mechanism in the thymus and the marrow.
GO ID:
GO Title:
Ideas Grants 2019
Internal Reference ID:
GNT1186731
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of Queensland
Recipient ABN:
63 942 912 684
Grant Recipient Location
Suburb:
St Lucia
Town/City:
St Lucia
Postcode:
4072
State/Territory:
QLD
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
QLD
Postcode:
Country:
AUSTRALIA