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Grant Award View - GA40787
COZMOS: Phase I/Ib trial of COmbined 5'-aZacitidine and carboplatin for...
GA ID:
GA40787
Agency:
Department of Health and Aged Care
Approval Date:
29-Mar-2019
Publish Date:
26-Apr-2019
Category:
Medical Research
Grant Term:
1-Apr-2019 to 31-Mar-2022
Value (AUD):
$125,354.50
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
DoHAC 18/19 1.1 Health and Medical Research
Grant Program:
2018_MRFF Rare Cancers Rare Diseases, Unmet Need_commencing_2018
Grant Activity:
COZMOS: Phase I/Ib trial of COmbined 5'-aZacitidine and carboplatin for recurrent/refractory paediatric brain and solid tuMOurs
Purpose:
Survival for children with relapsed and recurrent brain tumours is poor, and there have been few new treatment options. However, recent research shows that these tumours have a general change in their DNA (methylation), and altering methylation may stop the tumours. This international trial will test the safety of treating children with ependymoma with a methylation inhibitor (azacitidine) and a standard chemotherapy drug (carboplatin), in the first step of exploring this new treatment option.
GO ID:
GO Title:
Medical Research Future Fund Clinical Trials Activity – Rare Cancers, Rare Diseases and Unmet Need Grant Opportunity
Internal Reference ID:
MRF1170019
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
Clayton
Town/City:
Clayton
Postcode:
3800
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW, VIC, SA, WA, QLD
Postcode:
Multiple
Country:
AUSTRALIA