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Grant Award View - GA29105-V3
Lifespan-dependent molecular shaping of the T cell receptor repertoire
GA ID:
GA29105-V3
Agency:
Australian Research Council
Approval Date:
27-Nov-2018
Variation Publish Date:
20-Oct-2021
Variation Date:
12-Oct-2021
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
11-Feb-2019 to 10-Feb-2022
Value (AUD):
$575,000.00
(GST inclusive where applicable)
Varies:
GA29105
- Lifespan-dependent molecular shaping of the T cell receptor repertoire
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 18/19 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Lifespan-dependent molecular shaping of the T cell receptor repertoire
Purpose:
Mammals have an intricate and highly complex immune system, whose function alters throughout life. Why and how this occurs is very unclear however, yet remains a crucial question. This project aims to provide fundamental knowledge on how the human lifespan shapes specific T cell receptors and determine molecular mechanisms underlying gain-of-function and loss-of-function during immunologically distinct phases of life. This project will provide analysis of multi-dimensional, high throughput datasets to identify fundamental links between the transcriptional landscape and TCR signatures across human lifespan, thus will significantly answer key immunological questions in the field.
GO ID:
GO Title:
Discovery Projects commencing in 2019
Internal Reference ID:
DP19 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
The University of Melbourne
Recipient ABN:
84 002 705 224
Grant Recipient Location
Suburb:
UNIVERSITY OF MELBOURNE
Town/City:
UNIVERSITY OF MELBOURNE
Postcode:
3010
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
3010
Country:
AUSTRALIA