To access this element change to forms mode OFF
Grant Award View - GA215407-V1
An investigation into CD1a, a versatile antigen-presenting molecule
GA ID:
GA215407-V1
Agency:
Australian Research Council
Approval Date:
19-Jan-2022
Variation Publish Date:
4-Jul-2023
Variation Date:
30-May-2023
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
1-Dec-2022 to 30-Nov-2025
Value (AUD):
$574,386.00
(GST inclusive where applicable)
Varies:
GA215407
- An investigation into CD1a, a versatile antigen-presenting molecule
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 21/22 Discovery
Grant Program:
Discovery Projects
Grant Activity:
An investigation into CD1a, a versatile antigen-presenting molecule
Purpose:
This project aims to investigate how T lymphocytes are activated by lipids presented by the skin-associated antigen-presenting molecule, CD1a. Using X-ray crystallography and cellular immunology, we will provide fundamental insight into this poorly understood immunological axis. We will determine the molecular basis for how CD1a presents diverse self and foreign lipids, and how such CD1a-lipid complexes are recognised by the responding T cells. This basic science discovery project will provide substantial new knowledge in the burgeoning field of lipid-mediated immunity, which should ultimately lead to new therapies targeting the CD1a lipid display molecule to either prevent immune mediated damage or promote protective immunity as required.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2022
Internal Reference ID:
DP22 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
MULGRAVE
Town/City:
MULGRAVE
Postcode:
3170
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
3170
Country:
AUSTRALIA