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Grant Award View - GA59376
Understanding parasite ubiquitination to generate novel antimalarials
GA ID:
GA59376
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
1-Aug-2019
Publish Date:
17-Oct-2019
Category:
Medical Research
Grant Term:
1-Jan-2020 to 31-Dec-2024
Value (AUD):
$703,725.05
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 19/20 1.1 Health and Medical Research
Grant Program:
Investigator
Grant Activity:
Understanding parasite ubiquitination to generate novel antimalarials
Purpose:
Malaria remains the most serious and widespread parasitic disease in humans. As parasites show increasing resistance to the frontline treatments, we need potent antimalarial drugs with new modes of action. My project proposes a new method of drug treatment that can be adapted to specifically target parasites. I will initially identify and then activate parasite protein complexes known the E3 ubiquitin ligases, using drugs known as PROTACs, to ultimately degrade key parasite proteins.
GO ID:
GO Title:
Investigator Grants 2019
Internal Reference ID:
GNT1177431
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Walter and Eliza Hall Institute of Medical Research
Recipient ABN:
12 004 251 423
Grant Recipient Location
Suburb:
Parkville
Town/City:
Parkville
Postcode:
3052
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
Country:
AUSTRALIA