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Grant Award View - GA147139
Relaxin receptor structural determination to aid therapeutic development
GA ID:
GA147139
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
26-Nov-2020
Publish Date:
18-Jan-2021
Category:
Health and Medical Research
Grant Term:
1-Jan-2021 to 31-Dec-2024
Value (AUD):
$1,266,601.60
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 19/20 1.1 Health and Medical Research
Grant Program:
Ideas
Grant Activity:
Relaxin receptor structural determination to aid therapeutic development
Purpose:
The receptor for the peptide hormone relaxin, RXFP1, is being targeted by numerous drug companies for the treatment of cardiovascular disease. However, the lack of molecular detail of how relaxin binds and activates RXFP1 is hindering new drug development. We will determine the structure of the complex of relaxin bound to RXFP1 and the mechanism by which this activates cells. The knowledge gained will aid in the design of new drugs targeting RXFP1 for the treatment of cardiovascular disease.
GO ID:
GO Title:
2020 Ideas Grants
Internal Reference ID:
GNT2001027
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of Melbourne
Recipient ABN:
84 002 705 224
Grant Recipient Location
Suburb:
Parkville
Town/City:
Parkville
Postcode:
3052
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
Country:
AUSTRALIA