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Grant Award View - GA205206
Glioblastoma - inhibition of P2X7R as a potential therapeutic target for...
GA ID:
GA205206
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
3-Nov-2021
Publish Date:
13-Dec-2021
Category:
Medical Research
Grant Term:
1-Jan-2022 to 31-Dec-2025
Value (AUD):
$842,094.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 20/21 1.1 Health and Medical Research
Grant Program:
Ideas Grants
Grant Activity:
Glioblastoma - inhibition of P2X7R as a potential therapeutic target for treatment of this aggressive cancer.
Purpose:
Glioblastoma is a highly fatal human brain cancer generally affecting young adults, with survival time of only 12 months after diagnosis despite treatment. Our work is showing very promising results where inhibiting a particular cell membrane protein, P2X7R (with a particular drug AZ10606120) can significantly reduce tumour proliferation. AZ10606120 was better than the currently available chemotherapy, Temozolomide. This is very exciting and warrants urgent further study via this Ideas grant.
GO ID:
GO Title:
2021 Ideas Grants
Internal Reference ID:
2021/GNT2011590
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
Clayton
Town/City:
Clayton
Postcode:
3800
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
ACT, VIC
Postcode:
Multiple
Country:
AUSTRALIA