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Grant Award View - GA64826-V2
A thermodynamic pathway to intracellular delivery
GA ID:
GA64826-V2
Agency:
Australian Research Council
Approval Date:
4-Dec-2019
Variation Publish Date:
20-Oct-2021
Variation Date:
12-Oct-2021
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
6-Jul-2020 to 5-Jul-2023
Value (AUD):
$505,000.00
(GST inclusive where applicable)
Varies:
GA64826
- A thermodynamic pathway to intracellular delivery
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 19/20 Discovery
Grant Program:
Discovery Projects
Grant Activity:
A thermodynamic pathway to intracellular delivery
Purpose:
Cells transmit information through molecules. By delivering foreign molecules into cells, such as DNA and proteins, it is possible to engineer and reprogram cells just like a computer. This proposal aims to develop a novel microfluidic device for intracellular delivery. The device will work by exposing cells to rapid thermal shock to generate transient disruptions in cell membranes and thereby enable influx of foreign molecules into cells. To understand how the method can be optimized, the thermodynamic pathway of membrane disruption will be investigated at a single cell level. The methods and insights arising from this project could eventually lead to novel, patentable and lower-cost health technologies.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2020
Internal Reference ID:
DP20 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
University of Technology Sydney
Recipient ABN:
77 257 686 961
Grant Recipient Location
Suburb:
ULTIMO
Town/City:
ULTIMO
Postcode:
2007
State/Territory:
NSW
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW
Postcode:
2007
Country:
AUSTRALIA