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Grant Award View - GA83511
The TiNT Trial: A phase II clinical trial of trametinib in paediatric...
GA ID:
GA83511
Agency:
Department of Health and Aged Care
Approval Date:
14-May-2020
Publish Date:
15-Jun-2020
Category:
Health and Medical Research
Grant Term:
1-Jun-2020 to 31-May-2025
Value (AUD):
$761,210.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
DoHAC 19/20 1.1 Health Policy Research and Analysis
Grant Program:
2019_MRFF_RCRDUN_Childhood_Brain_Cancer_2020
Grant Activity:
The TiNT Trial: A phase II clinical trial of trametinib in paediatric patients with neurofibromatosis type 1 associated progressive optic pathway gliomas
Purpose:
Neurofibromatosis type 1 (NF1) is a genetic disorder in children that can sometimes result in the development of a brain tumour in the optic nerves (Optic Pathway Gliomas, OPG). The TiNT clinical trial will discover if trametinib - a targeted therapy that is effective in some cancers - can be used to treat children with NF1-associated OPG. We will investigate if trametinib can reduce the size of the tumours as well as improve vision, quality of life, behaviour and neurodevelopment.
GO ID:
GO Title:
MRFF Clinical Trials Activity – RCRDUN Initiative – 2019 Childhood Brain Cancer Grant Opportunity
Internal Reference ID:
MRF1199564
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Monash University
Recipient ABN:
12 377 614 012
Grant Recipient Location
Suburb:
Clayton
Town/City:
Clayton
Postcode:
3800
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
NSW, VIC, SA, WA, QLD, Overseas
Postcode:
Multiple
Country:
AUSTRALIA, NEW ZEALAND