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Grant Award View - GA204233
TARGETING DEREGULATED EPIGENETIC MECHANISMS IN LYMPHOMA
GA ID:
GA204233
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
3-Nov-2021
Publish Date:
6-Dec-2021
Category:
Medical Research
Grant Term:
1-Jan-2022 to 31-Dec-2025
Value (AUD):
$1,111,758.80
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 20/21 1.1 Health and Medical Research
Grant Program:
Ideas Grants
Grant Activity:
TARGETING DEREGULATED EPIGENETIC MECHANISMS IN LYMPHOMA
Purpose:
Diffuse large B-cell lymphomas (DLBCL) are aggressive tumors, with 40% patients not responding to the conventional chemotherapy treatment or relapsing after treatment. In this proposal, we will evaluate new epigenetic therapies to treat these lymphomas, targeting the non-inherited environmental factors that control the function of genes. We predict that the results from this project will drive new clinical trials for DLBCL patients with TET2 or CREBBP mutations, which represent 1 in 3 patients.
GO ID:
GO Title:
2021 Ideas Grants
Internal Reference ID:
2021/GNT2011217
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
University of Melbourne
Recipient ABN:
84 002 705 224
Grant Recipient Location
Suburb:
Parkville
Town/City:
Parkville
Postcode:
3052
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
ACT, VIC, Overseas
Postcode:
Multiple
Country:
AUSTRALIA, UNITED STATES