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Grant Award View - GA1341
Mechanism of proteotoxic stress induced type I interferon signalling and...
GA ID:
GA1341
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
19-Jul-2017
Publish Date:
6-Feb-2018
Category:
Medical Research
Grant Term:
1-Jan-2018 to 31-Dec-2021
Value (AUD):
$359,912.84
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 16/17 1.1 Health and Medical Research
Grant Program:
Early Career Fellowships
Grant Activity:
Mechanism of proteotoxic stress induced type I interferon signalling and implications for human disease
Purpose:
All cells have a proteasome system to degrade unwanted proteins. Proteasome dysfunction causes a build-up of proteins that triggers, through an unknown mechanism, activation of the immune system leading to inflammation. People with mutations in genes which code for proteasome activity experience a severe disease known as Proteasome-Associated Autoinflammatory Syndrome. We aim to elucidate the link between protein aggregation and immune activation and employ this knowledge in disease treatment.
Internal Reference ID:
GNT1143412
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Walter and Eliza Hall Institute of Medical Research
Recipient ABN:
12 004 251 423
Grant Recipient Location
Suburb:
Parkville
Town/City:
Parkville
Postcode:
3052
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
Country:
AUSTRALIA