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Grant Award View - GA215287

How novel ribosomal RNA gene repeat variants drive cellular function

Contact Details

ARC NCGP General Enquiries

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02 6287 6600

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GA ID:
GA215287
Agency:
Australian Research Council
Approval Date:
25-Jan-2022
Publish Date:
25-Jan-2022
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
25-Jan-2022 to 31-Dec-2024
Value (AUD):
$637,955.00 (GST inclusive where applicable)

One-off/Ad hoc:
No
Aggregate Grant Award:
No

PBS Program Name:
ARC 21/22 Discovery
Grant Program:
Discovery Projects
Grant Activity:
How novel ribosomal RNA gene repeat variants drive cellular function
Purpose:
The hundreds of ribosomal RNA gene repeat copies are a remarkable part of our genomes, as they encode the machinery responsible for all cellular protein synthesis and shape the structure of the nucleus. However, due to their high degree of sequence similarity, they still have not been assembled into the human genome reference. This project will resolve this impasse and furthermore uncover the functional impacts of a newly identified molecular diversity in the ribosomal RNA gene repeats. Outcomes include new paradigms for how the ribosomal RNA gene repeats drive protein synthesis and genome structure, and a blueprint to develop novel genomics applications for human health, biotechnology, and agriculture.

GO ID:
GO Title:
Discovery Projects for funding commencing in 2022
Internal Reference ID:
DP22 Round 1
Selection Process:
Targeted or Restricted Competitive

Confidentiality - Contract:
No
Confidentiality - Outputs:
No

Grant Recipient Details

Recipient Name:
The Australian National University
Recipient ABN:
52 234 063 906

Grant Recipient Location

Suburb:
ACTON
Town/City:
ACTON
Postcode:
2601
State/Territory:
ACT
Country:
AUSTRALIA

Grant Delivery Location

State/Territory:
ACT
Postcode:
2601
Country:
AUSTRALIA

Contact Details

ARC NCGP General Enquiries

:
02 6287 6600

: