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Grant Award View - GA214553-V1
Unravelling the mechanisms of sodium-selectivity in biological ion...
GA ID:
GA214553-V1
Agency:
Australian Research Council
Approval Date:
14-Jan-2022
Variation Publish Date:
4-Jul-2023
Variation Date:
20-Jun-2023
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
22-Aug-2022 to 21-Aug-2025
Value (AUD):
$364,813.00
(GST inclusive where applicable)
Varies:
GA214553
- Unravelling the mechanisms of sodium-selectivity in biological ion channels
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 21/22 Discovery
Grant Program:
Discovery Projects
Grant Activity:
Unravelling the mechanisms of sodium-selectivity in biological ion channels
Purpose:
The aim of this project is to determine the origins of protein-mediated sodium ion transport across cell membranes. The project expects to reveal the mechanisms of selective ion conduction in different sodium-selective ion channels using advanced computer simulations, in concert with non-canonical mutation experiments that target the roles of protein chemistry. The expected outcome is improved understanding of how proteins discriminate between ion species, challenging theories that have stood for decades. The results should provide benefits in the form of basic understanding relevant to ion transport phenomena in biology and novel materials, with atomic-level views of nervous system function to guide future directions in drug development.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2022
Internal Reference ID:
DP22 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
RMIT University
Recipient ABN:
49 781 030 034
Grant Recipient Location
Suburb:
MELBOURNE
Town/City:
MELBOURNE
Postcode:
3000
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
3000
Country:
AUSTRALIA