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Grant Award View - GA30261

Transforming the treatment landscape in elderly Acute Myeloid Leukaemia

Contact Details

NHMRC Research Help Centre

:
1800 500 983

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GA ID:
GA30261
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
25-Oct-2018
Publish Date:
21-Dec-2018
Category:
Medical Research
Grant Term:
1-Jan-2019 to 31-Dec-2022
Value (AUD):
$1,071,166.00 (GST inclusive where applicable)

One-off/Ad hoc:
No
Aggregate Grant Award:
No

PBS Program Name:
NHMRC 17/18 1.1 Health and Medical Research
Grant Program:
Project
Grant Activity:
Transforming the treatment landscape in elderly Acute Myeloid Leukaemia
Purpose:

The majority of patients with AML are elderly and unfit for intensive chemotherapy. Standard low-intensity therapy is generally unsuccessful and survival short-lived. We have recently led ground-breaking studies showing that targeting the cell-survival machinery with the BCL-2 inhibitor venetoclax in combination with chemotherapy is an exciting therapeutic prospect. We have now identified two non-overlapping mechanisms of resistance to this regimen amendable to combination with novel inhibitors.


GO ID:
GO Title:
NHMRC Project Grant Scheme
Internal Reference ID:
GNT1162809
Selection Process:
Targeted or Restricted Competitive

Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property

Grant Recipient Details

Recipient Name:
Monash University
Recipient ABN:
12 377 614 012

Grant Recipient Location

Suburb:
Clayton
Town/City:
Clayton
Postcode:
3800
State/Territory:
VIC
Country:
AUSTRALIA

Grant Delivery Location

State/Territory:
VIC, Overseas
Postcode:
Multiple
Country:
AUSTRALIA, NEW ZEALAND, UNITED STATES

Contact Details

NHMRC Research Help Centre

:
1800 500 983

: