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Grant Award View - GA30174
Minor class splicing: A therapeutic target for pancreatic cancer?
GA ID:
GA30174
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
25-Oct-2018
Publish Date:
21-Dec-2018
Category:
Medical Research
Grant Term:
1-Jan-2019 to 31-Dec-2021
Value (AUD):
$781,867.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
NHMRC 17/18 1.1 Health and Medical Research
Grant Program:
Project
Grant Activity:
Minor class splicing: A therapeutic target for pancreatic cancer?
Purpose:
Our goal is to identify a chemical inhibitor that will be highly effective against a group of difficult to treat solid tumours that carry mutations in a gene called KRAS. These tumours include pancreatic cancer, which has an abysmal 5-year survival rate. We have shown that an Achilles' heel for KRAS-driven tumours is a process called minor class splicing. By identifying an inhibitor that blocks this process specifically, we expect to obstruct the growth of cancer without harming healthy tissues.
GO ID:
GO Title:
NHMRC Project Grant Scheme
Internal Reference ID:
GNT1161336
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property
Grant Recipient Details
Recipient Name:
Walter and Eliza Hall Institute of Medical Research
Recipient ABN:
12 004 251 423
Grant Recipient Location
Suburb:
Parkville
Town/City:
Parkville
Postcode:
3052
State/Territory:
VIC
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
VIC
Postcode:
Country:
AUSTRALIA