To access this element change to forms mode OFF
Grant Award View - GA215284
The Epigenetics of Sex in the Dragon
GA ID:
GA215284
Agency:
Australian Research Council
Approval Date:
25-Jan-2022
Publish Date:
25-Jan-2022
Category:
Science, Technology, Engineering and Mathematics (STEM) Research
Grant Term:
25-Jan-2022 to 31-Dec-2025
Value (AUD):
$1,257,021.00
(GST inclusive where applicable)
One-off/Ad hoc:
No
Aggregate Grant Award:
No
PBS Program Name:
ARC 21/22 Discovery
Grant Program:
Discovery Projects
Grant Activity:
The Epigenetics of Sex in the Dragon
Purpose:
Genetic codes do not directly translate to phenotypes -- environment acts through epigenetics to modify development. We use advanced molecular techniques to examine how epigenetics responds to temperature to reverse sex in our novel animal model, the dragon lizard. How does the cell sense temperature? Once the extrinsic signal is captured, how does it influence chromatin modification to release or suppress key genes in the sex differentiation pathway? Which sex genes are targets? Epigenetic enzymes are astonishingly conserved, providing exciting opportunities to draw from human systems to unravel novel signatures of temperature-induced sex switching in reptiles. This project will advance knowledge of developmental programming generally.
GO ID:
GO Title:
Discovery Projects for funding commencing in 2022
Internal Reference ID:
DP22 Round 1
Selection Process:
Targeted or Restricted Competitive
Confidentiality - Contract:
No
Confidentiality - Outputs:
No
Grant Recipient Details
Recipient Name:
University of Canberra
Recipient ABN:
81 633 873 422
Grant Recipient Location
Suburb:
BRUCE
Town/City:
BRUCE
Postcode:
2617
State/Territory:
ACT
Country:
AUSTRALIA
Grant Delivery Location
State/Territory:
ACT
Postcode:
2617
Country:
AUSTRALIA