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Grant Award View - GA30110

Epigenetic reprogramming of monocytes by BCG vaccination

Contact Details

NHMRC Research Help Centre

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1800 500 983

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GA ID:
GA30110
Agency:
National Health and Medical Research Council (NHMRC)
Approval Date:
25-Oct-2018
Publish Date:
21-Dec-2018
Category:
Medical Research
Grant Term:
1-Jan-2019 to 31-Dec-2021
Value (AUD):
$1,092,078.05 (GST inclusive where applicable)

One-off/Ad hoc:
No
Aggregate Grant Award:
No

PBS Program Name:
NHMRC 17/18 1.1 Health and Medical Research
Grant Program:
Project
Grant Activity:
Epigenetic reprogramming of monocytes by BCG vaccination
Purpose:

Some vaccines can have non-specific beneficial effects. One example is the Tuberculosis vaccine called 'BCG', which not only confers protection against TB, but a range of infections. This effect is mediated by the innate immune system, which is thought to have no memory. However, accumulating evidence suggests that innate immune cells can remember certain exposures, such as the BCG vaccine, by changing how their DNA is packaged. This re-packaging of DNA alters the cell response to infections.


GO ID:
GO Title:
NHMRC Project Grant Scheme
Internal Reference ID:
GNT1157556
Selection Process:
Targeted or Restricted Competitive

Confidentiality - Contract:
Yes
Confidentiality Reason(s) - Contract:
Privacy Act 1988
Intellectual property
Confidentiality - Outputs:
Yes
Confidentiality Reason(s) - Outputs:
Intellectual property

Grant Recipient Details

Recipient Name:
Murdoch Childrens Research Institute
Recipient ABN:
21 006 566 972

Grant Recipient Location

Suburb:
Parkville
Town/City:
Parkville
Postcode:
3052
State/Territory:
VIC
Country:
AUSTRALIA

Grant Delivery Location

State/Territory:
VIC
Postcode:
Country:
AUSTRALIA

Contact Details

NHMRC Research Help Centre

:
1800 500 983

: